CAR T-Cell Therapy in Max Hospital

CAR T-cell therapy emerges as a groundbreaking frontier in the battle against cancer, tapping into the body’s immune system to combat the disease. This transformative treatment involves the meticulous modification and reprogramming of a patient’s T-cells, integral components of the immune system, enabling them to identify and attack specific cancer cells. At the forefront of innovation, Max Institute of Musculoskeletal Sciences & Orthopaedics is championing this revolutionary approach, providing a beacon of hope in the realm of cancer treatment.

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Simplified Breakdown of CAR T-Cell Therapy:

The process initiates with the extraction of a patient’s T-cells through leukapheresis. These T-cells undergo genetic engineering in a laboratory, introducing chimeric antigen receptors (CARs) designed to recognize cancer-specific antigens. The modified T-cells, now equipped for targeted action, are multiplied and infused back into the patient’s bloodstream. The CARs guide these T-cells to recognize and bind to cancer cells, triggering an immune response that leads to the destruction of the cancer cells. Importantly, some engineered T-cells persist as “memory” cells, offering potential long-term immunity against cancer.

Who is the Right Candidate for CAR T-Cell Therapy?

The ideal candidate for CAR T-cell therapy typically presents with blood cancer, such as acute lymphoblastic leukaemia (ALL) or diffuse large B-cell lymphoma (DLBCL). Specific antigen expression on cancer cells, failure of previous treatments, and an overall suitability assessment contribute to identifying eligible candidates.

Contraindications for CAR T-Cell Therapy:

Certain contraindications, including severe organ dysfunction, active infections, and specific neurological conditions, guide the selection of suitable candidates for this intricate therapy.

Preparation Before CAR T-Cell Therapy:

A comprehensive patient evaluation, leukapheresis for cell collection, genetic modification of T-cells, and their expansion in the laboratory form the preparatory phases. Patient-specific characteristics and cancer details guide the process.

Procedure:

Lymphodepletion, involving chemotherapy to create space for infused CAR T-cells, precedes the actual CAR T-cell infusion. Close monitoring follows to address potential side effects, including cytokine release syndrome and neurologic toxicities.

Precautions and Aftercare:

Proactive management of side effects, infection prevention measures, and prescription of preventive medications contribute to successful aftercare. As with any medical intervention, careful monitoring and responsive action ensure patient well-being.

Key Benefits of CAR T-Cell Therapy:

CAR T-cell therapy boasts remarkable efficacy, precise targeting of cancer cells, potential for long-term remission, diverse applications beyond blood cancers, and improved survival rates. Despite challenges such as managing side effects and addressing costs, the therapy heralds a new era in cancer treatment.

The Future of CAR T-Cell Therapy:

Ongoing research aims to refine the technique, broaden its applicability to solid tumors, and enhance accessibility. Incorporation of CRISPR, a gene-editing therapy, and the recent approval of cellular therapy for non-cancerous conditions by the US FDA underscore the evolving landscape of cell and gene therapy.

Conclusion:

CAR T-cell therapy stands as a beacon of hope, showcasing unprecedented success in specific cancer types and unveiling new possibilities for patients with limited treatment options. Max Institute of Musculoskeletal Sciences & Orthopaedics remains at the forefront, driving innovation and transforming the narrative of cancer treatment. In the ever-evolving journey against cancer, CAR T-cell therapy illuminates a path of promise and potential.

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Dr. Harit Chaturvedi

Specialist:      Surgical Oncologist
Experience:   25+ years of experience
Hospital:        Max Hospital Saket

About Doctor:

• Harit Chaturvedi is a famous surgical Oncologist at Max Super Speciality Hospital, Saket, New Delhi.
• Having a vast 25 years of experience in the field of surgical Oncologist.
• Chaturvedi has performed surgeries at live surgical workshops and has been championing the cause for cancer awareness.

Dr. Aditi Chaturvedi

SPECIALIST : Surgical Oncologist
Experience :    9 years of experience
Hospital :         Max Hospital Saket

About Doctor:

• Dr. Aditi Chaturvedi is a surgical oncologist with 8+ years of experience.
• Her clinical interest includes breast and oncoplastic surgery, colorectal cancer surgery, esophageal cancer surgery and head and neck reconstruction surgery.
• She won Gold Medal in General Surgery from AIIMS, New Delhi and has vice chancellor’s Certificate of Merit from MUHS, Nashik.

Dr. Raman Deep Singh Arora

Specialist :      Pediatric Oncologist
Experience :   22 years of experience
Hospital :         Max Hospital Saket

About Doctor:

• Dr. Raman Deep Singh Arora is a renowned Paediatric Oncologist and Pediatrician, with experience of over 20 years.
• He offers treatment of all types of cancers in children including Leukemia, Lymphoma, Brain Tumor, Embryonic Tumor, Sarcoma etc.
• He is honored with the membership of various prestigious associations such as Children’s Cancer and Leukemia Group, UK, Indian Cooperative Oncology Network, India, International Society of Paediatric Oncology, Netherlands, Royal College of Pediatrics and Child Health, UK.

Dr. Rajender Kumar

Specialist:    Oncologist
Experience: 22 years of experience
Hospital:      Max Hospital Saket

About Doctor:

• Dr. Rajender Kumar is a renowned Cancer Specialist at Max Super Specialty Hospital, Saket, New Delhi.
• He specializes in treating all kinds of cancers including Head, Neck, Gallbladder, Ovaries, Skin, Pancreas, Small & Large Intestine, Prostate, Lungs, Breast, And Liver.
• He is an expert in Immunotherapy, Chemotherapy, Targeted Therapy, Lymphoma & Myeloma diagnosis and treatment.

Dr. Akshay Tiwari

Speciality:   Surgical Oncologist
Experience: 18 years of experience
Hospital:      Max Hospital Saket

About Doctor:

• Dr. Akshay Tiwari is a musculoskeletal surgical oncologist with 18+ years of experience.
• He received Best Published Paper award at RGCON; Best Paper Award at ICC and Gold Medal of highest marks in Anatomy in MBBS exams.
• He has performed more than 1000 surgeries for patients suffering from bone and soft tissue and tumors.

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We offers these Services

• Providing a doctor’s opinion and proper quotation
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• Providing help in money exchanging
• Providing free local sim card
• Arranging video consultation with specialist doctor if case requires

Dr. Sandeep Batra

Specialist:         Medical Oncologist
Experience:     16+ years of experience
Hospital:           Max Hospital Saket

About Doctor:

• Dr. Sandeep Batra is a renowned Medical Oncologist and carries an experience of more than a decade.
• Dr. Sandeep Batra qualified & experienced in management of all types of cancers
• Dr. Sandeep Batra’s Interests are in the management of Lung Cancer, Breast cancer, Colorectal cancers, Genitourinary cancers including Cervical cancer, Ovarian Cancer, Kidney cancer, Bladder cancer, Prostate cancer, Myeloma, Lymphoma, Leukemia and Sarcomas

Dr. Durgatosh Pandey

Specialist:     Surgical Oncologist
Experience:  18+ years of experience
Hospital:       Max Hospital Saket

About Doctor:

• Dr. Durgatosh Pandey is a surgical oncologist with 18+ years of experience.
• Dr. Durgatosh Pandey has written a book on science and philosophy “A Peep into Void”.
• Dr. Durgatosh Pandey is a founder member of the Lung Cancer Consortium Asia, Esophageal cancer consortium, trustee member of ICON (Indian Co-operative Oncology Network), External examiner for M.Ch (Surgical Oncology) examination at Tata Memorial Hospital, Mumbai and member of the ICMR Task Force.

Dr. Devavrat Arya

Speciality:          Oncologist
Experience:       17+ Years Experience
Hospital:            Max Hospital Saket

About doctor:

• Dr. Devavrat Arya is a highly skilled Medical Oncologist and Oncologist in Delhi.
• He holds an experience of 15 years in the medical field.
• He has done his DM – Medical Oncology from Gujarat University, India in 2011, MD – Internal Medicine from Gujarat University, India in 2006 and MBBS from University of Delhi in 2001.

Dr. Charu Garg

Speciality:        Radiation Oncology and  Oncologist
Experience:      24+ Years Experience
Hospital:           Max Hospital Saket  

About doctor:

• A specialist in Radiation Oncology with a rich experience of over 24 years is currently working in Max Super Speciality Hospital, Saket.
•  She has handled numerous complex medical cases and is known for attention to detail, accurate diagnosis and treating patients with empathy.Connect to Dr Charu Garg for priority appointments and a hassle-free experience via the medical experts.

Dr. Dodul Mondal

Speciality:        Radiation Oncology and  Consultant
Experience:     13+ Years Experience
Hospital:           Max Hospital Saket

About doctor:

•  Dr. Dodul Mondal is a well-known Radiation Oncologist with 13+ years of experience.
• He has experience of working with Proton Beam Therapy at one of the largest university hospitals in the United States. 
• He is highly experienced with Tomotherapy, Stereotactic RadioSurgery (SRS), Stereotactic Radiation Therapy (SRT), Stereotactic Body Radiotherapy (SBRT), Image Guided Radiotherapy (IGRT), Intensity Modulated Radiotherapy (IMRT), Rapid Arc, VMAT etc. 

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• Providing a doctor’s opinion and proper quotation
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• Providing help in money exchanging
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• Arranging video consultation with specialist doctor if case requires

Max Hospital Saket Delhi

Number of beds:   500
ICU Beds:                 267
Airport Distance: 13 KM

About Hospital:

• Max Super Speciality Hospital at Saket is one of the topmost healthcare service
• Providers in India. The multi-super speciality hospital has a capacity of over 500 beds, 250 functional beds. It is equipped with state-of-the-art facilities, advanced technologies.
• With the help of over 300 leading specialist Doctors, strong nursing staff, and state-of-the-art innovative medical tools.