Treatment of Sickle Cell Anemia in Delhi

Treatment of Sickle Cell Anemia

Sickle cell anemia, an hereditary blood disorder, transforms the normal structure of red blood cells, causing them to shift from their typical round and flexible form to rigid, adhesive sickled cells. This alteration hinders the effective transport of oxygen across the body, impeding the vital role of red blood cells. Additionally, sickled cells possess a reduced lifespan compared to healthy red blood cells, which results in the breakdown of these cells and subsequently leads to anemia. Dr. Vikas Dua treat Sickle Cell Disease in Children, including the blood and provides the best Sickle Cell Anemia treatment in Delhi NCR .

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Individuals afflicted by sickle cell anemia persistently encounter life-threatening medical complications.

What is the cause of sickle cell anemia?

According to Doctor for Sickle Cell Anemia in Delhi indicates that this condition is inherited from biological parents. Sickle cell anemia arises from a mutation in the gene responsible for producing normal red blood cells. Individuals with this disorder inherit the mutated hemoglobin protein gene from both parents, while those with sickle cell trait inherit the mutated gene from one parent.

Symptoms: Typically manifesting as early as six months of age, the symptoms of sickle cell anemia exhibit variation among individuals and evolve over time. These signs and symptoms encompass:

Anemia: Sickle cells are prone to premature disintegration and death. Unlike normal red blood cells, which have a lifespan of around 120 days before renewal, sickle cells tend to perish within 10 to 20 days, leading to a shortage of red blood cells (anemia). The body’s oxygen supply becomes inadequate due to this shortfall, resulting in fatigue.
Painful Episodes: Frequent and severe pain episodes characterize sickle cell anemia. The abnormal, sickle-shaped red blood cells impede blood flow, causing pain in the chest, abdomen, and joints through narrow blood vessels. This leads to recurring painful episodes, sometimes necessitating hospitalization. The intensity and duration of the pain vary, ranging from a few hours to several days. While some individuals experience only a few pain episodes annually, others endure dozens or more. Severe pain crises may require hospitalization. In certain adolescents and adults with sickle cell anemia, chronic pain can contribute to bone and joint damage.
Swelling in Hands and Feet: The obstruction of blood flow by sickle-shaped red blood cells can lead to swelling in the hands and feet.
Increased Susceptibility to Infections: Sickle cells can impair the spleen’s function, rendering it more vulnerable to infections. Infants and children with sickle cell anemia commonly receive vaccinations and antibiotics to prevent potentially fatal infections like pneumonia.
Delayed Growth and Puberty: Insufficient healthy red blood cells can delay infant and child development, as well as puberty in teenagers.
Stroke-like Symptoms: Reduced blood flow and blockages in cerebral blood vessels can result in symptoms resembling those of a stroke.

Risk Factors: For a child to be born with sickle cell anemia, both parents must carry the sickle cell gene. In the United States, sickle cell anemia predominantly affects individuals of African, Mediterranean, and Middle Eastern descent. In India, it is particularly prevalent among tribal populations, notably in states such as Chattisgarh, Odisha, Jharkhand, Madhya Pradesh, and upper Assam.

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Prevention: Consulting a genetic counselor before attempting to conceive can provide insights into the risk of having a child with sickle cell anemia if one carries the sickle cell trait. Genetic counselors can also discuss preventive measures and reproductive options.

Diagnosis: The presence of the hemoglobin type responsible for sickle cell anemia can be identified through a blood test called HPLC. This test is routinely conducted during pregnancy in major centers across India. It is advisable for both partners to undergo HPLC tests before attempting to conceive.

Treatment: The objectives of treating sickle cell anemia include averting pain episodes, alleviating symptoms, and preventing complications. Treatment options encompass medications and blood transfusions. Hematopoietic stem cell transplantation, commonly known as a bone marrow transplant, serves as a curative approach for certain children and teenagers who experience recurrent painful episodes and acute strokes.

Medications: Daily medication usage reduces the frequency of painful episodes and may diminish the necessity for blood transfusions and hospital stays. Recent advancements have introduced targeted medications for treating sickle cell disease in adults and children aged twelve and above. When taken orally, these medications can mitigate the risk of anemia while enhancing overall blood circulation. Pain relief medication is employed during sickle cell pain episodes, with doctors sometimes prescribing narcotics to alleviate discomfort. Adequate hydration is crucial to prevent pain episodes.

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Fortis Memorial Research Institute

Number of beds:   1000
ICU Beds:     298
Airport Distance:  17 KMs

Brief About:

Fortis Memorial Research Institute was established in 2001.
It is an outstanding multi-speciality quaternary care hospital,having the top-notch infrastructure, advanced equipment, highly qualified and experienced medical professionals and super sub-specialists.
Fortis Hosptial Gurgaon is an advanced centre of excellence in Robotic Surgery, Neurosciences, Oncology, Renal Sciences, BMT, Organ Transplants, Orthopaedics, Cardiac Sciences and Obstetrics & Gynaecology.

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JCI & NABH Accredited Hospital, NABL Accredited Lab, NABH Certified Nursing Excellence, NABH Accredited Blood Bank
FMRI is a 1000 bedded and 15 Operation theaters and over 400 diagnostics centres (including JVs).
Medical facility endowed with a dedicated team of 200 world-renowned doctors, covering a number of specialities, who aim to provide the best quality medical care to all the patients, national as well as international.
This hospital is well set up with the latest technologies and equipment throughout all the specialties and research labs, which are accredited by NABL.
This ensures that the patients at FMRI receive diagnostic results and treatment with high accuracy and in minimum time.
With a vision for the community, FMRI operates various speciality clinics such as, for Paediatrics, Nephrology, Neurology, Gynecology, Orthopedics, Oncology and many more, which provide long term healthcare management and follow up care.
FMRI is the premium healthcare provider and endeavours to be known as the “Mecca of Medicine” – the ultimate healthcare destination.

Dr. Rahul Bhargava

Specialist: Hematologic Oncologist, BMT
Experience: 23+ years of experience
Hospital: Fortis Memorial Research Institute

About Doctor:

Rahul Bhargava is a Leading Haemato-oncologist in India with over 23+ years of experience.
He has performed 100+ adult bone marrow transplants which are record-breaking in the whole of North India.
He is a Director of Haematology & Bone Marrow Transplant at Fortis Memorial Research Institute hospital, Gurgaon.

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He has successfully completed 400+ transplants to his credit.
Brings along with him an International experience; worked in Vancouver, Canada where he specifically trained in Umbilical cord transplant.
Member of various prestigious organizations, American Society of Bone Marrow Transplant, American Society of Paediatric Haemato-Oncology, International Society of Paediatric Oncology to name a few.
During his extensive career, Dr. Bhargava has dealt with enumerable adult and paediatric patients suffering from a wide range of Congenital and Acquired ailments. This includes Acute and Chronic blood conditions such as Blood Cancers, bleeding disorders along with inherited immune deficiency syndromes and metabolic disorders.
He is the first Indian doctor to perform and propagate a Stem Cell Transplant procedure for patients suffering from Multiple Sclerosis
The first Haploidentical Stem Cell Transplant in Gurgaon was performed by him on a patient suffering from Fanconi Anaemia patient

Dr. Vikas Dua

Specialist: Pediatric Oncologist
Experience: 15 years of experience
Hospital: Fortis Memorial Research Institute

About Doctor:

Dr Vikas Dua is one the leading consultants in the field of Pediatric- Hemato-oncology & bone marrow transplant.
He has an experience of over 21+ years and has performed several successful BMTs for thalassemia and leukaemia cases for children from India, Afghanistan, Iraq and African Countries.
Dr. Dua has completed his MBBS & MD (Paediatrics) from PGIMS, Rohtak .Following which he did his Fellowship in DNB (Paediatrics) from Sri Ganga Ram.

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He has also done his Advanced Fellowship in Pediatric Bone Marrow Transplant from National University Hospital, Singapore and also did his training in child BMT from the renowned, St. Jude’s Children research Hospital Memphis
Dr Vikas Dua bagged many national and international awards for his outstanding work in Paediatrics BMT
Dr Dua has his expertise in paediatric haematology and bone marrow transplantation.

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Get Opinion From India’s Best Doctors

We offers these Services

Providing a doctor’s opinion and proper quotation
Selecting the best hospital and doctor as per your case
Arranging a call with the doctor (if the case required)
Visa assistance, Providing Visa Invitation Letter (VIL)
Providing full guidance how to get Visa from your country
Providing total cost including treatment, air tickets, accommodation, and food
Assitance to book flight ticket from your country
Arranging airport pick up/ drop
Providing professional language interpreter
Booking accommodation and guest house as per your budget/ prefrence
Providing help in money exchanging
Providing local sim card
Arranging video consultation with specialist doctor if case requires

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